Interaction between Cialis and Dapoxetine

Some men who suffer from erectile dysfunction want not only to restore their erection but also to prolong sexual intercourse. Often, it is difficult to achieve such an effect with just Cialis; however, when combining Cialis and dapoxetine, reaching this goal becomes more realistic.

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Cialis is a selective inhibitor of phosphodiesterase 5 (PDE-5). The drug helps to restore an erection by affecting the smooth-muscle structures of the penis. Dapoxetine is a drug designed for prolonging sexual intercourse. Patients can safely take Cialis with dapoxetine, since the drugs have a normal interaction.

Notably, upon interaction with Cialis, the effect of Dapoxetine is increased and the man is able to completely restore his sexual power. However, the long-term use of these drugs requires a preliminary test be completed for contraindications; furthermore, constant monitoring by an andrologist should be done.

Cialis helps to restore an erection and maintain it for 24 hours to 36 hours. The active component of the drug (tadalafil) has high absorption values and, accordingly, the therapeutic effect after taking the pill presents quickly.

Dapoxetine’s action is also very fast. The active component of the drug is absorbed quickly enough and begins to act on average one hour to two hours after taking the pill.

When taking both Cialis and Dapoxetine, the following should occur:

  • High duration of sexual intercourse: according to reviews, dapoxetine helps to increase the duration of sexual intercourse by an average of 50% to 70%
  • Strong erection: tadalafil is rapidly absorbed and helps to restore potency approximately 20 minutes to 60 minutes after taking the pill.

The advantage of Cialis over other inhibitors of PDE-5 is that its therapeutic effect persists throughout the day. Conversely, for example, Viagra (Pfizer, New York, NY, USA) ceases to work after two hours to four hours.

Rules for combining dapoxetine and Cialis

Simultaneous use of these stimulant medications is allowed only if there is a direct prescription for their combination provided by the attending physician.

Basic recommendations for use:

  1. These drugs should be taken preferably one hour to two hours prior to sexual intercourse
  2. No more than one tablet of Cialis and dapoxetine (20 mg of tadalafil and 60 mg of dapoxetine hydrochloride) should be consumed per day
  3. The patient should swallow the pills entirely, without breaking them into pieces or chewing them
  4. Alcohol consumption should be limited on the day of usage of these drugs

Contraindications

Simultaneous use of Cialis and dapoxetine to maintain an erection and increase libido is prohibited within six months after an attack of ischemic stroke or myocardial infarction. Usage of these drugs is also prohibited when taking the following:

  • Alpha-adrenoblockers
  • Nitrate-containing substances

The pairing of Cialis with dapoxetine should not be done in patients with conditions like:

  • Disorders of the digestive system
  • Renal and hepatic insufficiency
  • Biventricular heart failure
  • Oncological lesions
  • Arterial hypertension
  • Structural disorders of the genital organs after Peyronie’s disease, fibrotic changes, and acquired distortions
  • Hypersensitivity to the drugs’ components

Brief information about dapoxetine

Dapoxetine is a medication that is widely used in the treatment of premature ejaculation in men.
The active component of the drug is dapoxetine hydrochloride. The substance blocks specific receptors in the brain of the man, thereby delaying ejaculation. The effect of the drug is based on the absorption of serotonin.